Integrative analyses of single-cell transcriptome and regulome using MAESTRO

摘要

An overview of the MAESTRO workflow. Starting from fastq files, MAESTRO performs pre-processing, alignment, quality control, expression index for scRNA-seq, peak calling for scATAC-seq, clustering, differential analysis, cell-type annotation, and transcription factor identification analysis. If scRNA-seq and scATAC-seq from the same experiment are given, MAESTRO can perform the integration analysis and annotate the integrated clusters