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Intravitreal Voriconazole for Treatment of Bilateral Endogenous Candida Chorioretinitis

机译:玻璃体内伏荷佐唑治疗双侧内源性念珠菌性胆小炎

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摘要

This report describes a patient with bilateral endogenous candida chorioretinitis. The patient had a 2-day history of bilateral blurred vision. Fundus photography revealed multiple chorioretinal infiltrations in both eyes and a parafoveal hemorrhage in the left eye. After 2 days, fundus examination showed an increased number of infiltrations and hemorrhages in both eyes and worsening vitreous inflammation. A large infiltrative intraretinal lesion and a retinal hemorrhage of the left eye were discovered on optical coherence tomography. Candida albicans was diagnosed from blood culture. The bilateral candida chorioretinitis had not responded to systemic or topical antifungal medication. The chorioretinitis was refractory to intravitreal amphotericin B as well. Intravitreal voriconazole injection in both eyes and intravitreal bevacizumab injection in the left eye were performed thereafter. The chorioretinal infiltrations and hemorrhages decreased in both eyes. Intravitreal voriconazole injection was effective in the treatment of intractable candida chorioretinitis.
机译:本报告描述了双侧内源性念珠菌患者的患者。患者有两天的双边模糊视觉历史。眼底拍摄在眼睛和左眼中的剖面性出血中揭示了多种潜冲渗透。 2天后,眼底考试表明眼睛渗透数量增加和玻璃体炎症恶化的渗透数和出血。在光学相干断层扫描上发现了一种大的渗透性静脉曲张病变和左眼视网膜出血。念珠菌被诊断出血液培养。双侧念珠菌胆肠炎没有反应全身或局部抗真菌药物。 ChorioreTinitis也是含有玻璃体内两性蛋白B的难治性。此后,进行眼睛和玻璃体玻璃纤维素注射术中的玻璃体内voriconazole注射。双眼中的官期渗透和出血减少。玻璃体内伏立康唑注射在治疗难治性的念珠菌性胆小血管炎方面是有效的。

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