A novel multistage antiplasmodial inhibitor targeting Plasmodium falciparum histone deacetylase 1

摘要

SI, selectivity index, which was calculated by the EC50 for HepG2 or 293T/EC50 for 3D7, a drug-sensitive strain of P. falciparum. Dd2 is another P. falciparum strain resistant to several antimalarial drugs, including mefloquine, pyrimethamine, and chloroquine.