首页> 美国卫生研究院文献>Cardiovascular Diabetology >Correction to: Combination therapy with pemafibrate (K-877) and pitavastatin improves vascular endothelial dysfunction in dahl/salt-sensitive rats fed a high-salt and high-fat diet
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Correction to: Combination therapy with pemafibrate (K-877) and pitavastatin improves vascular endothelial dysfunction in dahl/salt-sensitive rats fed a high-salt and high-fat diet

机译:校正至:用Pemafibrate(K-877)和Pitavastatin的组合治疗改善了DAHL /盐敏感大鼠的血管内皮功能障碍喂养高盐和高脂饮食

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摘要

Effects of pitavastatin, pemafibrate or combination of pitavastatin and pemafibrate on endothelium-dependent vascular relaxations in response to acetylcholine. Rats were fed a normal diet (ND) or a high-salt and high-fat diet (HD). The rats were divided into five groups and treated with a vehicle, pitavastatin, pemafibrate (K-877), or combination of pitavastatin and pemafibrate. Data are expressed as the mean ± SD. *P < 0.001, HD-vehicle group versus ND-vehicle group. #P < 0.05, HD-combination group versus HD-vehicle group. Number of rats in each group: ND-vehicle, n = 4; HD-vehicle, n = 5; HD-pitavastatin, n = 5; HD-pemafibrate, n = 5; and HD-combination, n = 5. Statistical analysis was performed using mixed effect model with a Bonferroni post-hoc test
机译:岩浆盆样素,Pemafibrate或Pitavastatin与Pemafibrate对乙酰胆碱依赖于乙酰胆碱的内皮依赖性血管弛豫的影响。大鼠喂养正常饮食(Nd)或高盐和高脂饮食(HD)。将大鼠分为五组,并用载体,匹伐他汀,Pemafibrate(K-877)或脱抗属和Pemafibrate的组合处理。数据表示为平均值±SD。 * P <0.001,高清车组与ND-载体组。 #p <0.05,HD组合组与高清车辆组。每组大鼠数量:Nd-载体,n = 4;高清车辆,n = 5; HD-pitavastatin,n = 5; HD-Pemafibrate,n = 5;和高清组合,n = 5.使用混合效应模型进行统计分析,通过HOC测试后的Bonferroni进行

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