Skeleton optimization of neuronal morphology based on three-dimensional shape restrictions

摘要

The computational workflow of skeleton optimization. The first stage is the preprocessing of the skeleton for optimization. The first stage is to interpolate the digital skeleton to increase the points and extract a branch from the digital skeleton; this includes steps 1 to 3. The second stage is digital skeleton optimization, which includes steps 4 and 5. The last stage is to output the neuron morphology file