Performance evaluation of lossy quality compression algorithms for RNA-seq data

摘要

In recent years, high-throughput genome sequencing has become an essential tool in biomedical and medical research with a wide range of applications in basic biomedical research, clinical diagnostic, drug discovery, forensic medicine, etc. The fast growing applications of genomic data have produced a large amount of sequencing data, for which efficient and effective data compression technologies are desired to cope with the corresponding growth in data storage and transmission costs.