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Paradoxical bronchospasm: a rare adverse effect of fenoterol use

机译:矛盾的支气管痉挛:FENoterol使用的罕见不良影响

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摘要

Paradoxical bronchospasm refers to the constriction of the airways after treatment with a sympathomimetic bronchodilator. Theoretically, bronchodilators, such as beta‐agonist inhalers, act to ease asthma symptoms by relaxing the muscles surrounding the walls of the bronchial tubes, which relieve bronchial constriction. However, in rare instances, some patients develop respiratory distress or even respiratory failure after inhaled bronchodilator use, although the exact mechanism for this adverse effect is unknown. We report a male, with a known asthma history diagnosed for more than one decade, receiving fenoterol (Berotec®) for wheezing control and the worsening of his clinical condition immediately after bronchodilator administration.
机译:矛盾的支气管痉挛是指用慰问性支气管扩张剂处理后气道的收缩。理论上,诸如β-激动剂吸入器等支气管扩张剂,通过放松支气管围绕支气管壁的肌肉来缓解哮喘症状,这缓解支气管收缩。然而,在罕见的情况下,有些患者在吸入支气管扩张剂使用后发育呼吸窘迫甚至呼吸衰竭,尽管这种不良影响的确切机制是未知的。我们报告了一只雄性,具有已知的哮喘历史,诊断为十多个十年,接受FENoterol(Berotec®),用于喘息控制,并在支气管扩张剂施用后立即立即恶化他的临床状况。

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