1320. Pharmacokinetics of Isavuconazole Administered as Isavuconazonium Sulfate Intravenous Solution via Nasogastric Tube or Orally in Healthy Volunteers

摘要

Nasogastric (NG) tube feeding is most common in the intensive care unit and is also used for cancer patients who are unable to eat (e.g. patients with mucositis) or do not want to eat due to severe nausea1. For such critically ill patients with invasive fungal infections, administration of isavuconazonium sulfate (ISAVUSULF) via NG tube can be an alternate route of drug administration.