AMPAkines potentiate the corticostriatal pathway to reduce acute and chronic pain

摘要

Experimental design and location of intracranial viral injections and cannula placements. a Schematic for in vivo optogenetic targeting of the PL and AMPAkine treatment in the NAc. b Histologic expression of Channelrhodopsin (ChR2) in the PL. c Representative brain slice showing the intracranial infusion site in the NAc core. d Schematic showing tip of injectors in the NAc core