Auer rods in mixed phenotype acute leukemia T/myeloid: A report of three cases

摘要

The morphologic features of blasts in cases of MPAL with Auer rods. A: There are two blast populations from case #1: the first population is large sized (green arrow) with cytoplasmic granules. The second population is small to medium sized with scanty cytoplasm without granules (pink arrow). B: Auer rods are identified in the first blast population (red arrow) in case #1. C-D: Some blasts have distinct Auer rods (red arrow) in the bone marrow and peripheral blood smears respectively (Wright-Giemsa stain) from case #2. E: Cytochemical stains demonstrate strong myeloperoxidase activity among these blasts (green arrow) in case #2. F: Myeloperoxidase granules are identified in the blast cells from case #2 by electronic microscopy (green arrow). G: Blasts in case #3 are intermediate to large sized with round nuclei, dispersed to variably condensed chromatin and small amounts of cytoplasm. H-I: Auer rods are identified in a subset of blasts in Case #3.