A randomized trial of vorinostat with treatment interruption after initiating antiretroviral therapy during acute HIV-1 infection

摘要

A randomized, open-label pilot study in individuals treated with antiretroviral therapy (ART) since acute HIV infection (AHI) with a regimen including a histone deacetylase inhibitor to induce HIV from latency and control HIV replication during subsequent treatment interruption (TI).