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Pediatric Vaccine Hesitancy and the Utilization of Antibody Measurements: A Novel Strategy with Implications for COVID 19

机译:儿科疫苗犹豫不决抗体测量的利用:一种新的策略对Covid 19的影响

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摘要

Vaccine hesitancy is a well researched area with implications for both public health and the health of children and their families The factors leading to vaccine hesitancy are often complex and involve fear of the healthcare system and the process of vaccine development, cultural viewpoints and experiences. Pediatric patients often rely on parental guidance and decision making, and this may result in a lack of immunization for some children. The availability of the COVID 19 vaccine has been widely anticipated, yet not all individuals will seek the vaccine. Once vaccines are available for children under the age of 16 years, this long-standing pediatric management issue may again emerge and impact public health. The clinical trial efficacy and safety data for children and adolescents less than 16 years of age are not yet available. A traditional approach is to discuss the concerns of the parent in relationship to presentation and review of American Association of Pediatrics (AAP) and CDC guidelines in the framework of medical and scientific explanations. This includes the presentation of efficacy and safety data. Therefore, the use of lab-based antibody testing adds scientific evidence and emphasizes the need for vaccination against SARS CoV-2 and other pathogens. The purpose of this commentary is to propose lab-based testing as a potential adjunctive strategy in addressing this public health concern. Further study of a pediatric population is required to assess the impact of the selective use of lab-based testing in improving vaccination rates among a pediatric population.
机译:疫苗犹豫不决是一个有关公共卫生和儿童健康影响的高层区域,他们的家庭导致疫苗犹豫不决的因素往往是复杂的,并且涉及担心医疗保健系统和疫苗发展过程,文化观点和经验。儿科患者往往依靠父母的指导和决策,这可能导致某些孩子缺乏免疫。 Covid 19疫苗的可用性已被广泛预期,但并非所有个人都会寻求疫苗。一旦疫苗可用于16岁以下的儿童,这种长期的儿科管理问题可能会再次出现并影响公共卫生。尚未提供不到16岁儿童和青少年的临床试验疗效和安全数据。一种传统的方法是讨论父母在医疗和科学解释框架中对美国儿科(AAP)和CDC指南的介绍和审查的关系。这包括疗效和安全数据的呈现。因此,使用基于实验室的抗体测试增加了科学证据,并强调需要针对SARS COV-2和其他病原体的疫苗接种。该评论的目的是将基于实验室的测试提出作为解决这一公共卫生问题的潜在辅助战略。需要进一步研究儿科人群,以评估选择性使用基于实验室的测试在提高儿科人群中的疫苗接种率方面的影响。

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