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Comparative study on pharmacokinetics and toxicity of intravitreal and sub-Tenon injection of triamcinolone acetonide in ocular tissues

机译：玻璃体内和亚肾上腺素注射眼组织中抗菊酮酮的药代动力学和毒性的比较研究

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摘要

To compare the differences in kinetics, distribution, and toxicity of triamcinolone acetonide (TA) between the injection methods, sub-Tenon and intravitreal injections in rabbit ocular tissues.

机译：比较兔眼组织中的注射方法，子榫和玻璃体内注射术之间的动力学，分布和毒性的差异，分布和毒性（TA）。

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期刊名称 International Journal of Ophthalmology
作者
Yuko Arie; Hiroko Miyai; Ayako Suzuki; Takeshi Okabe; Mitsuyo Takashima; Mayumi Takata; Takashi Kurasawa; Masaki Ito; Reijiro Arakawa; Yuichiro Ogura; Akira Naito;
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作者单位

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年(卷),期 2020(13),12
年度 2020
页码 1864–1871
总页数 8
原文格式 PDF
正文语种
中图分类眼科学;
关键词
corticosteroid(s); pharmacokinetics; injection; ophthalmic drug delivery; toxicity;

机译：皮质类固醇;药代动力学;注射;眼科药物递送;毒性;

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专利

1. Determination of triamcinolone acetonide in silicone oil and aqueous humor of vitrectomized rabbits' eyes: Application for a pharmacokinetic study with intravitreal triamcinolone acetonide injections (Kenalog? 40) [J] . Fernandes-CunhaG.M., SalibaJ.B., SiqueiraR.C., Journal of Pharmaceutical and Biomedical Analysis: An International Journal on All Drug-Related Topics in Pharmaceutical, Biomedical and Clinical Analysis . 2014,第Null期

机译：玻璃化兔子眼睛硅油和房水中曲安奈德的测定：玻璃体内注射曲安奈德（Kenalog？40）在药代动力学研究中的应用
2. Photodynamic therapy combined with intravitreal bevacizumab and sub-tenon triamcinolone acetonide injections for age-related macular degeneration [J] . YoshizawaC., SaitoW., HiroseS., Japanese Journal of Ophthalmology . 2013,第1期

机译：光动力疗法联合玻璃体内贝伐单抗和肌腱下曲安奈德注射液治疗老年性黄斑变性
3. Pharmacokinetic study of vitreous and serum concentrations of triamcinolone acetonide after posterior sub-Tenon's injection [J] . KovacsK., WagleyS., QuirkM.T., American Journal of Ophthalmology: The International Journal of Ophthalmology . 2012,第5期

机译：Tenon后注射后玻璃体和血清中曲安奈德的药代动力学研究
4. Mathematical Modeling of Triamcinolone Acetonide Drug Release from the I-vation Intravitreal Implant (A Controlled Release Platform) [C] . Peter J. Barnett Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2009

机译：抗菊酮酮丙酮酮类药物释放的数学建模从I-vation玻璃体植入物（控制释放平台）
5. Effect of intravitreal or sub-tenon triamcinolone acetonide injection at completion of vitrectomy on peripheral retinochoroidal thickness in eyes with proliferative diabetic retinopathy [D] . Fujiwara Yoshito, 藤原圭人 2019

机译：玻璃体切除术完成后玻璃体内或肌腱下注射丙酮酸曲安奈德对增生性糖尿病性视网膜病变的眼睛周围脉络膜脉络膜厚度的影响
6. Comparison between intravitreal bevacizumab and posterior sub-tenon injection of triamcinolone acetonide in macular edema secondary to retinal vein occlusion [O] . Meng-Ju Tsai, Yi-Ting Hsieh, Yi-Jie Peng 2018

机译：玻璃体腔注射贝伐单抗和后腱膜下注射曲安奈德治疗视网膜静脉阻塞引起的黄斑水肿的比较
7. Effect of posterior sub-tenon injection of triamcinolone acetonide as ‎an adjunct therapy to intravitreal anti-vascular endothelial growth ‎factor in the management of diabetic macular oedema [O] . Ahmed Ali Ayoub, hosny mohammad, hasan bayomy 2020

机译：后胎酮丙酮酮酮的疗效作为玻璃体内抗血管内皮生长因子的辅助疗法在糖尿病性黄斑水肿管理中的辅助疗法

Comparative study on pharmacokinetics and toxicity of intravitreal and sub-Tenon injection of triamcinolone acetonide in ocular tissues

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