Advances and perspectives in discovery and functional analysis of small secreted proteins in plants

摘要

Plant SSPs can be derived from protein precursors, which can be either nonfunctional or functional, or translated from small open reading frames (sORFs). SSPs derived from functional protein precursors often contain an N-terminal signal sequence (NSS), which is removed during maturation. SSPs synthesized from nonfunctional precursors can be further divided into three categories: post-translationally modified (PTM) SSPs, Cys-rich SSPs, and non-Cys-richon-PTM SSPs. In addition, SSPs can be encoded by sORFs that locate at upstream of main ORFs (uORFs), in transcripts of long non-coding RNAs (lncRNAs), or primary transcripts of miRNAs (pri-miRNAs). Adapted from ref. 11