100-year-old Haematologica images: Hodgkin and Reed-Sternberg cells in needle aspiration of the spleen

摘要

The color drawings reproduced on the cover of this issue of Haematologica have been taken from a 1932 article published by Paolo Introzzi, at that time a young assistant of Adolfo Ferrata at the Department of Internal Medicine of the University of Pavia and subsequently Editor in Chief of Haematologica from 1960 to 1973.1 In this paper, Introzzi describes four patients with splenomegaly and without superficial adenomegalies in whom the diagnosis of Hodgkin disease had been made through the cytological study of spleen aspirates. The procedure was without side effects. A few weeks later there was involvement of superficial lymph nodes and the diagnosis of Hodgkin disease was confirmed by their histological examination.