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The Structural Understanding of Transthyretin Misfolding and the Inspired Drug Approaches for the Treatment of Heart Failure Associated With Transthyretin Amyloidosis

机译：Transthyretin错误折叠的结构理解及其对促rentretin淀粉样蛋白症相关的心力衰竭治疗心力衰竭的启发性药物方法

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期刊名称 Frontiers in Pharmacology
作者
Shan He; Xinyue He; Lei Liu; Wenbo Zhang; Lanlan Yu; Zhun Deng; Zhang Feiyi; Shanshan Mo; Yue Fan; Xinyue Zhao; Lun Wang; Chenxuan Wang; Shuyang Zhang;
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作者单位

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年(卷),期 2021(-1),-1
年度 2021
页码 -1
总页数 9
原文格式 PDF
正文语种
中图分类药学;
关键词
Transthyretin; amyloidal aggregation; protein structural stabilizers; cardiac amyloidosis; protein folding;

机译：Transthyretin;淀粉样蛋白聚集;蛋白质结构稳定剂;心脏淀粉样蛋白病;蛋白质折叠;

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专利

1. Cyclodextrin, a novel therapeutic tool for suppressing amyloidogenic transthyretin misfolding in transthyretin-related amyloidosis [J] . Hidetoshi Arima, Hirofumi Jono, Keiichi Motoyama, The biochemical journal . 2011,第1期

机译：环糊精，一种抑制转甲状腺素相关淀粉样变性中淀粉样变性运甲状腺素蛋白错误折叠的新型治疗工具
2. Cyclodextrin, a novel therapeutic tool for suppressing amyloidogenic transthyretin misfolding in transthyretin-related amyloidosis [J] . Jono Hirofumi, Anno Takayuki, Motoyama Keiichi, The Biochemical Journal . 2011,第1期

机译：环糊精，一种新型的治疗工具，用于抑制与甲状腺素相关的淀粉样变性病中淀粉样变性甲状腺素的错折叠
3. Diagnosis and treatment of heart failure in hereditary transthyretin amyloidosis [J] . Gisela D. Puig-Carrion, Alex Reyentovich, Stuart D. Katz Clinical autonomic research: Official journal of the Clinical Autonomic Research Society . 2019,第Suppla1期

机译：遗传性Transthyretin淀粉样蛋白症心力衰竭的诊断和治疗
4. CHARACTERIZATION OF FIBRILLAR TRANSTHYRETIN IN EX VIVO CARDIAC DEPOSITS FROM CASES OF SENILE SYSTEMIC AMYLOIDOSIS [C] . J.S Kingsbury, R Theberge, C.E. Costello, International Symposium on Amyloidosis . 2008

机译：老年人淀粉样淀粉样蛋白症患者胎儿心脏沉积物中纤维序列的特征
5. The Role of Non-Coding Genetic Variants on Transthyretin Gene Transcription in Transthyretin Amyloidosis [D] . Boldbaatar, Batbold. 2022

机译：非编码遗传变异在促甲肾上腺素淀粉样蛋白症中的Transthyretin基因转录中的作用
6. Transthyretin Cardiac Amyloidosis: Pathogenesis Treatments and Emerging Role in Heart Failure with Preserved Ejection Fraction [O] . Van-Khue Ton, Monica Mukherjee, Daniel P Judge 2014

机译：运甲状腺素蛋白淀粉样变性病：保留射血分数的心力衰竭的发病机制治疗和新兴作用。
7. Transthyretin Cardiac Amyloidosis: Pathogenesis, Treatments, and Emerging Role in Heart Failure with Preserved Ejection Fraction [O] . Van-Khue Ton, Monica Mukherjee, Daniel P. Judge 2014

机译：Transthyretin心脏淀粉样蛋白症：病理发生，治疗和在心力衰竭中具有保存的射血分数的作用

The Structural Understanding of Transthyretin Misfolding and the Inspired Drug Approaches for the Treatment of Heart Failure Associated With Transthyretin Amyloidosis

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