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Safety Tolerability and Pharmacokinetics of Ibuprofenamine Hydrochloride Spray (NSAIDs) a New Drug for Rheumatoid Arthritis and Osteoarthritis in Healthy Chinese Subjects

机译：布洛芬胺盐酸盐喷雾（NSAIDS）的安全性耐受性和药代动力学用于中风关节炎和骨关节炎的新药在健康的中国科目中

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摘要

Ibuprofenamine hydrochloride spray is novel transdermal nonsteroidal anti-inflammatory drugs (NSAIDs), under clinical development for the treatment of Rheumatoid Arthritis and Osteoarthritis as a novel transdermal drug.

机译：布洛芬胺盐酸盐喷雾是新型透皮非甾体抗炎药（NSAIDS），在临床开发下，用于治疗类风湿性关节炎和骨关节炎作为一种新型透皮药物。

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期刊名称 Drug Design Development and Therapy
作者
Panpan Xie; Wei Xue; Wenyuan Qi; Yang Li; Lei Yang; Zhaojun Yang; Aixin Shi;
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作者单位

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年(卷),期 2021(-1),-1
年度 2021
页码 -1
总页数 10
原文格式 PDF
正文语种
中图分类药学 ; 药物化学 ;
关键词
ibuprofenamine hydrochloride spray; tolerability; safety; pharmacokinetics;

机译：布酚甲苯甲胺盐酸盐喷雾;可耐受性;安全;药代动力学;

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专利

1. Pharmacokinetics, Safety and Tolerability of ABT-494, a Novel Selective JAK 1 Inhibitor, in Healthy Volunteers and Subjects with Rheumatoid Arthritis [J] . Mohamed Mohamed-Eslam F., Camp Heidi S., Jiang Ping, Clinical pharmacokinetics . 2016 ,第12期

机译：新型选择性JAK 1抑制剂ABT-494在健康志愿者和类风湿关节炎患者中的药代动力学，安全性和耐受性
2. Pharmacokinetics, Safety and Tolerability of Tylerdipine Hydrochloride, a Novel Dihydropyridine Dual L/T-type Calcium Channel Blocker, after Single and Multiple Oral Doses in Healthy Chinese Subjects [J] . Zhou Sufeng, Wang Yuanyuan, Wang Lu, Clinical drug investigation . 2019 ,第1期

机译：盐酸泰越海胆盐酸盐的药代动力学，安全性和耐受性，一种新型二氢吡啶双L / T型钙通道阻断剂，在健康中受试者中单一和多剂量剂量之后
3. Safety, tolerability and pharmacokinetics of phenoprolamine hydrochloride floating sustained-release tablets in healthy Chinese subjects. [J] . Zhao L, Yang X, Xu R International Journal of Pharmaceutics . 2009 ,第1a2期

机译：盐酸吩洛拉明浮动缓释片在中国健康人群中的安全性，耐受性和药代动力学。
4. No adverse physiological responses to infrared whole body hyperthermia in patients with rheumatoid arthritis and ankylosing spondylitis compared to healthy subjects. [C] . F.G.J. OOSTERVELD, E. KOOPMAN, J. OLDE SCHOLTENHUIS, Advances in biomedical research . 2010

机译：与健康受试者相比，类风湿性关节炎和强直性脊柱炎患者对红外全身热疗没有不利的生理反应。
5. Pharmacokinetic / pharmacodynamic / disease progression model of drug effects in a rat model of rheumatoid arthritis. [D] . Lon, Hoi Kei. 2013

机译：类风湿关节炎大鼠模型中药物作用的药代动力学/药效动力学/疾病进展模型。
6. Tolerability Safety Pharmacokinetics and Drug Interaction of Cefotaxime Sodium–Tazobactam Sodium Injection (6:1) Following Single and Multiple Intravenous Doses in Chinese Healthy Subjects [O] . Ning Chen, Lu-Ning Sun, Wen-Hui Hu, 2020

机译：在中国健康受试者中单次和多种静脉剂量之后Cefotaxime钠-Tazobactam钠注射率（6：1）的可耐受性安全性药代动力学和药物相互作用
7. Safety, tolerability, pharmacokinetics, and efficacy of AMG 403, a human anti-nerve growth factor monoclonal antibody, in two phase I studies with healthy volunteers and knee osteoarthritis subjects [O] . 2015

机译：在一项针对健康志愿者和膝盖骨关节炎受试者的两项I期研究中，人抗神经生长因子单克隆抗体AMG 403的安全性，耐受性，药代动力学和功效

Safety Tolerability and Pharmacokinetics of Ibuprofenamine Hydrochloride Spray (NSAIDs) a New Drug for Rheumatoid Arthritis and Osteoarthritis in Healthy Chinese Subjects

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