Treatment of Severe Acute Bacterial Keratitis in Rabbits Using Continuous Topical Ocular Instillation with Norvancomycin

机译：用诺维霉素连续局部眼滴注治疗兔的严重急性细菌角膜炎

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摘要

Efficacy of norvancomycin (NVCM) through continuous topical ocular instillation drug delivery (CTOIDD) system for treating severe acute bacterial keratitis infection with Staphylococcus aureus was investigated.

机译：研究了NeNvancomycin（NVCM）通过连续局部眼镜滴注药物递送（CTOIDD）系统，用于治疗与金黄色葡萄球菌的严重急性细菌角膜炎感染的药物递送（CTOIDD）体系。

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期刊名称 Drug Design Development and Therapy
作者
Wenxiang Lin; Libei Zhao; Qian Tan; Ding Lin;
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作者单位

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年(卷),期 2021(-1),-1
年度 2021
页码 -1
总页数 12
原文格式 PDF
正文语种
中图分类药学;药物化学;
关键词
severe acute bacterial keratitis; continuous topical instillation; eye drop; norvancomycin; rabbit eyes;

机译：严重的急性细菌角膜炎;连续局部滴注;滴眼液;诺维霉素;兔眼;

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专利

1. Comparative Assessment of Distribution Characteristics and Ocular Pharmacokinetics of Norvancomycin Between Continuous Topical Ocular Instillation and Hourly Administration of Eye Drop [J] . Wenxiang Lin, Libei Zhao, Xuetao Huang, Drug Design, Development and Therapy . 2020,第1期

机译：诺维霉素分布特征和眼药代动力学在连续局部眼滴注与小滴水施用时的比较评价
2. Comparative Study of Ocular Pharmacokinetics of Gatifloxacin Between Continuous Lavage and Hourly Topical Instillation in Rabbits [J] . Zhao Xin, Shen Xu, Zhang Xian, Cornea . 2018,第11期

机译：兔连续灌洗与每小时局部滴注在兔幼兰氧化物眼镜药代动力学的比较研究
3. Comparative study on ocular pharmacokinetics of gatifloxacin between continuous lavage and hourly topical instillation in rabbits [J] . Zhao Xin, Shen Xu, Zhang Xian, Investigative ophthalmology & visual science . 2018,第9期

机译：兔连续灌洗与每小时局部滴注的甘油辛膜眼镜药代动力学的比较研究
4. FABRICATION OF OCULAR INSERTS OF CIPROFLOXACIN HCL FOR THE TREATMENT OF BACTERIAL KERATITIS AND CONJUNCTIVITIS [C] . K. Kohli, A. All, N. Ahmad International symposium on controlled release of bioactive materials;Consumer diversified products conference . 2001

机译：盐酸环丙沙星眼插入物的制备治疗细菌性角膜和结膜炎。
5. Topical nanoparticulate formulation of drugs for ocular keratitis. [D] . Yang, Xiaoyan. 2015

机译：眼角膜炎药物的局部用纳米颗粒制剂。
6. Comparative Assessment of Distribution Characteristics and Ocular Pharmacokinetics of Norvancomycin Between Continuous Topical Ocular Instillation and Hourly Administration of Eye Drop [O] . Wenxiang Lin, Libei Zhao, Xuetao Huang, 2020

机译：连续局部滴眼和每小时滴眼液给药之间对新霉素的分布特征和眼药代动力学的比较评估
7. Topical 0.3% ciprofloxacin, norfloxacin, and ofloxacin in treatment of bacterial keratitis: a new method for comparative evaluation of ocular drug penetration. [O] . Diamond, J P, White, L, Leeming, J P, 1995

机译：局部用0.3％环丙沙星，诺氟沙星和氧氟沙星治疗细菌性角膜炎：一种比较评估眼药渗透性的新方法。
8. Acute Oral Toxicity Study in Rats A Primary Dermal and Ocular Irritation Study in Rabbits and A Dermal Toxicity Study in Rabbits. [R] . 1978

机译：大鼠急性口服毒性研究家兔原发性皮肤和眼部刺激研究及家兔皮肤毒性研究。

Treatment of Severe Acute Bacterial Keratitis in Rabbits Using Continuous Topical Ocular Instillation with Norvancomycin

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