Prognostic Significance of Interim Response Evaluation during Definitive Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma

摘要

We investigated the clinical significance of interim response evaluation during definitive chemoradiotherapy in locally advanced esophageal squamous cell carcinoma. Interim response was evaluated using adaptive CT images including primary esophageal lesion and lymph node. The reduction rate of tumor area or diameter was measured. Interim response correlated with complete response and survival rates. That is, the evaluation of tumor burden reduction during treatment may help predict patient prognosis.