The necroptotic cell death pathway operates in megakaryocytes but not in platelet synthesis

摘要

a vWF-positive liver megakaryocyte numbers per field of view (FOV) in P2 MlklWt/Wt (n = 5), MlklWt/D139V (n = 3) and MlklD139V/D139V (n = 7) mice. b Representative vWF staining of liver megakaryocytes (brown) from MlklWt/Wt, MlklWt/D139V and MlklD139V/D139V mice. Data represent mean ± s.d. Student’s unpaired t-test, ****P < 0.0001.