Tumor exosome promotes Th17 cell differentiation by transmitting the lncRNA CRNDE-h in colorectal cancer

摘要

A The characterization of serum-derived exosome was determined by transmission electron micrograph, and western blot analysis was used to detect positive exosomal markers. B The proportion of Th17 cells in the tumor-infiltrating T cells isolated from CRC patients was detected by flow cytometry. C The correlation between the expression of CRNDE-h in the serum-derived exosome from 42 CRC patients and the proportion of Th17 cells in tumor-infiltrating T cells. EXO exosome, EDS exosome depleted supernatant.