Circ_0000745 strengthens the expression of CCND1 by functioning as miR-488 sponge and interacting with HuR binding protein to facilitate the development of oral squamous cell carcinoma

摘要

Circ_0000745 was upregulated in OSCC tissues and cells. a The expression of circ_0000745 in OSCC tissues (n=64) and matched normal controls (n=64) was measured by qPCR. b The expression of circ_0000745 in HOK, Cal-27, SCC-25, SCC9 and HSC-3 cells was measured by qPCR. c Overall survival was analyzed by Kaplan-Meier plot and log-rank test, using the median value of circ_0000745 expression as the cut-off value. ***P<0.001