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CircNEIL3 promotes cervical cancer cell proliferation by adsorbing miR-137 and upregulating KLF12

机译:Circneil3通过吸附miR-137并上调KLF12来促进宫颈癌细胞增殖

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摘要

Screening of differentially expressed circRNAs in cervical cancer. a Analysis of differentially expressed circRNAs in cervical cancer based on {"type":"entrez-geo","attrs":{"text":"GSE90737","term_id":"90737"}}GSE90737 dataset detected by the long probe (30 nt) (Fold change > 2.0, P < 0.05 in t-test). b Analysis of differentially expressed circRNAs in cervical cancer based on {"type":"entrez-geo","attrs":{"text":"GSE90737","term_id":"90737"}}GSE90737 dataset detected by the short probe (20 nt) (Fold change > 2.0, P < 0.05 in t-test). c Validation of circRNAs in 20 pairs of cervical cancer tissues and para-carcinoma tissues via qRT-PCR. d The expression of hsa_circ_0071474 in the cervical cancer cell lines SiHa, C-4 I, C-33A, HeLa and the normal cervical epithelial cells End1/E6E7 was detected by qRT-PCR. *P < 0.05, **P < 0.01, ***P < 0.001
机译:宫颈癌差异表达晶体筛选的筛选。基于{“类型”:“entrez-geo”,“attrs”:{“text”:“gse90737”,“term_id”:“90737”}}基于晶癌中的差异表达的Circrnas分析探针(30nt)(折叠变化> 2.0,T检验中的P <0.05)。 B基于{“类型”:“attrez-geo”,“attrs”:{“text”:“gse90737”,“term_id”:“90737”}}基于依am癌症中的差异表达颈癌探针(20nt)(折叠变化> 2.0,T检验中的P <0.05)。通过QRT-PCR验证20对宫颈癌组织和对癌组织的CircrNA。 d通过QRT-PCR检测HSA_CIRC_0071474在宫颈癌细胞系SiHA,C-4 I,C-33A,HERA和正常宫颈上皮细胞END1 / E6E7中的表达。 * P <0.05,** P <0.01,*** P <0.001

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