Toxicity Reduction after Craniospinal Irradiation via Helical Tomotherapy in Patients with Medulloblastoma: A Unicentric Retrospective Analysis

摘要

Medulloblastoma (MB) is one of the most common pediatric brain tumors. Surgical resection, followed by radiotherapy (RT) and chemotherapy, are the standard of care for medulloblastoma patients. This retrospective analysis assesses the toxicity profile of different radiation techniques (Tomotherapy versus conventional radiotherapy technique) and estimates survival rates. Radiotherapy via Tomotherapy seems to be an efficacious treatment for patients with lower rates of acute upper gastrointestinal and central nervous system toxicities than conventional radiotherapy techniques.