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Pooled CRISPR screening in pancreatic cancer cells implicates co-repressor complexes as a cause of multiple drug resistance via regulation of epithelial-to-mesenchymal transition

机译：在胰腺癌细胞中汇集Crisprpr筛选将共压阻遏物复合物视为通过调节上皮对间充质转换的多种耐药性的原因

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The online version contains supplementary material available at 10.1186/s12885-021-08388-1.

机译：在线版本包含在10.1186 / s12885-021-08388-1中提供的补充材料。

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期刊名称 BMC Cancer
作者
Ryne C. Ramaker; Andrew A. Hardigan; Emily R. Gordon; Carter A. Wright; Richard M. Myers; Sara J. Cooper;
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作者单位

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年(卷),期 2021(-1),-1
年度 2021
页码 -1
总页数 13
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
Genome-wide screen; CRISPR; Pancreatic cancer; Drug resistance; ABCG2; HDAC1; Precision oncology;

机译：基因组屏幕;CRISPR;胰腺癌;耐药;ABCG2;HDAC1;精确肿瘤学;

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专利

1. Pooled CRISPR screening in pancreatic cancer cells implicates co-repressor complexes as a cause of multiple drug resistance via regulation of epithelial-to-mesenchymal transition [J] . Ramaker Ryne C., Hardigan Andrew A., Gordon Emily R., BMC Cancer . 2021,第1期

机译：在胰腺癌细胞中汇集Crispr筛选将共压阻遏物复合物视为通过调节上皮 - 间充质转换的多种耐药性的原因
2. Commentary on "Epithelial-to-Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer" [J] . Beach Jessica A., Bowtell David D. L. Cancer research: The official organ of the American Association for Cancer Research, Inc . 2016,第24期

机译：关于“上皮到间充质转化对胰腺癌耐药性的贡献”的评论
3. Alpha-1 Antitrypsin Induces Epithelial-to-Mesenchymal Transition, Endothelial-to-Mesenchymal Transition, and Drug Resistance in Lung Cancer Cells [J] . Dong-ming Wu, Teng Liu, Shi-hua Deng, OncoTargets and therapy . 2020,第2期

机译：α-1抗胰蛋白酶诱导上皮 - 间充质过渡，内皮 - 间充质转换，肺癌细胞中的耐药性
4. MULTI-SCALE MODELING OF CANCER CELL MIGRATION AND ADHESION DURING EPITHELIAL-TO-MESENCHYMAL TRANSITION [C] . Rachel Zielinski, Cosmin Mihai, Samir Ghadiali ASME summer bioengineering conference;SBC2011 . 2012

机译：上皮-间充质转化过程中癌细胞迁移和粘附的多尺度建模
5. Transcriptional regulation of genes associated with drug resistance and growth of pancreatic cancer cells by mucin 1. [D] . Nath, Sritama. 2013

机译：粘蛋白1对与耐药性和胰腺癌细胞生长有关的基因的转录调控。
6. Alpha-1 Antitrypsin Induces Epithelial-to-Mesenchymal Transition Endothelial-to-Mesenchymal Transition and Drug Resistance in Lung Cancer Cells [O] . Dong-ming Wu, Teng Liu, Shi-hua Deng, 2020

机译：Alpha-1抗胰蛋白酶诱导肺癌细胞上皮-间充质转化内皮-间充质转化和耐药性
7. Pooled CRISPR screening in pancreatic cancer cells implicates co-repressor complexes as a cause of multiple drug resistance via regulation of epithelial-to-mesenchymal transition [O] . Ryne C. Ramaker, Andrew A. Hardigan, Emily R. Gordon, 2021

机译：在胰腺癌细胞中汇集Crisprpr筛选将共压阻遏物复合物视为通过调节上皮对间充质转换的多种耐药性的原因

Pooled CRISPR screening in pancreatic cancer cells implicates co-repressor complexes as a cause of multiple drug resistance via regulation of epithelial-to-mesenchymal transition

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