Serial magnetic resonance imaging findings during severe attacks of familial hemiplegic migraine type 2: a case report

摘要

MRI obtained on day 2 did not reveal any acute intracranial abnormality. However, scattered, non-enhancing punctate T2-FLAIR hyperintensities in subcortical white matter were present bilaterally in the frontal lobes. Day 4: Diffuse DWI and T2-FLAIR hyperintensities throughout the left cerebral hemisphere cortices, most pronounced over the lateral convexity. Possible associated T2 shinethrough rather than restricted diffusion. Associated sulcal effacement from gyral swelling. Day 7:Diffuse DWI and T2-FLAIR hyperintensities throughout the left cerebral hemisphere cortices similar to the MRI findings obtained on day 4. Subtle hypointensity on ADC in left cerebral hemisphere cortices and posterior temporal lobe. Day 11: Diffuse DWI and T2-FLAIR hyperintensities throughout the left cerebral hemisphere cortices similar to previous MRI findings. Mild hypointensity on ADC in the left cerebral hemisphere corticesand temporal lobe is more prominent compared to previous MRIs. Day 15: Diffuse DWI and T2-FLAIR hyperintensities throughout the left cerebral hemisphere cortices similar to previous MRIs. Mild hypointensity on ADC in left cerebral hemisphere cortices is even more prominent compared to previous MRIs. Day 154:Previously demonstrated left cerebral hemisphere cortical swelling and restricted diffusion has resolved. No new parenchymal signal abnormality or abnormal enhancement. Scattered non-enhancing punctate T2-FLAIR hyperintensities were present in subcortical white matter of bilateral frontal lobes similar to the first MRI