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Anti-IL-4Ralpha monoclonal antibody dupilumab mimics ulcerative colitis: a case report

机译：抗IL-4ralpha单克隆抗体杜帕里米布模仿溃疡性结肠炎：案例报告

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a Endoscopic image of rectum is shown. b Mucosal tissue was biopsied in sigmoid colon and histological examination with hematoxylin and eosin staining is shown with a scale bar

机译：显示了直肠的内窥镜图像。 B粘膜组织在乙状结肠中活检，用血管氧基和曙红染色的组织学检查以秤棒示出

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期刊名称 BMC Gastroenterology
作者
Yosuke Shimodaira; So Takahashi; Katsunori Iijima;
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作者单位

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年(卷),期 2021(-1),-1
年度 2021
页码 -1
总页数 4
原文格式 PDF
正文语种
中图分类肠道病毒与肝炎病毒;肝及胆疾病;肠疾病;
关键词
Dupilumab; IL-4Ralpha; Ulcerative colitis;

机译：Dupilumab;IL-4rha;溃疡性结肠炎;

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专利

1. Anti-IL-4Ralpha monoclonal antibody dupilumab mimics ulcerative colitis: a case report [J] . Yosuke Shimodaira, So Takahashi, Katsunori Iijima BMC Gastroenterology . 2021,第1期

机译：抗IL-4rha单克隆抗体Dupilumab模拟溃疡性结肠炎：案例报告
2. Human Neutrophil Elastase Proteolytic Activity in Ulcerative Colitis Favors the Loss of Function of Therapeutic Monoclonal Antibodies [J] . Renata Curciarello, Toni Sobande, Samantha Jones, Journal of Inflammation Research . 2020,第3期

机译：溃疡性结肠炎中的人嗜嗜嗜菌酶蛋白水溶性活性有利于治疗单克隆抗体的功能丧失
3. Population Pharmacokinetics and Pharmacodynamics of SHP647, a Fully Human Monoclonal Antibody Against Mucosal Addressin Cell Adhesion Molecule-1 (anti-MAdCAM-1), in Patients With Ulcerative Colitis or Crohn's Disease [J] . Wang Yi, Marier J. F., Lavigne Jean, The American Journal of Gastroenterology . 2018,第Suppla2期

机译：SHP647的人口药代动力学和SHP647的药效动物，一种溃疡性结肠炎或克罗恩病的患者患有针对粘膜中粘膜粘附性细胞粘附分子-1（抗Madcam-1）的全人单克隆抗体
4. A Humanised Anti-IL-17BR Monoclonal Antibody with Wide Therapeutic Potential in Allergic Asthma, Ulcerative Colitis, Pulmonary Fibrosis and Pancreatic Cancer [C] . Seema Patel, Carolina Fernes, Richard Brown, PEGS . 2015

机译：一种抗IL-17BR单克隆抗体，过敏性哮喘，溃疡性结肠炎，肺纤维化和胰腺癌中具有宽治疗潜力
5. Characterization of Anti-Ricin Monoclonal Antibodies and the Construction of a Chimeric Murine-Human IgG2/K Anti-Ricin Monoclonal Antibody [D] . Vendramelli, Robert Matthew 2011

机译：抗蓖麻毒蛋白单克隆抗体的表征和鼠/人IgG2 / K嵌合抗蓖麻毒蛋白单克隆抗体的构建
6. Circulating immunoglobulin G1 antibody in patients with ulcerative colitis against the colonic epithelial protein detected by a novel monoclonal antibody. [O] . A Dasgupta, A Mandal, K M Das 1994

机译：通过新型单克隆抗体检测的溃疡性结肠炎患者针对结肠上皮蛋白的循环免疫球蛋白G1抗体。
7. Circulating immunoglobulin G1 antibody in patients with ulcerative colitis against the colonic epithelial protein detected by a novel monoclonal antibody. [O] . Dasgupta, A, Mandal, A, Das, K M 1994

机译：通过新型单克隆抗体检测的溃疡性结肠炎患者针对结肠上皮蛋白的循环免疫球蛋白G1抗体。
8. Novel approaches to cancer targeting using epitope-binding properties that mimic monoclonal antibodies [R] . 1998

机译：使用模拟单克隆抗体的表位结合特性的癌症靶向的新方法

Anti-IL-4Ralpha monoclonal antibody dupilumab mimics ulcerative colitis: a case report

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