Single wavelength measurements of absorption coefficientsbased on iso-pathlength point

摘要

In optical sensing, to reveal the chemical composition of tissues, themain challenge is isolating absorption from scattering. Mosttechniques use multiple wavelengths, which adds an error due to theoptical pathlength differences. We suggest using a unique measurementangle for cylindrical tissues, the iso-pathlength (IPL) point, whichdepends on tissue geometry only (specifically the effective radius).We present a method for absorption assessment from a single wavelengthat multiple measurement angles. The IPL point presented similaroptical pathlengths for different tissues, both in simulation andexperiments, hence it is optimal. Finally, invivo measurements validated our proposed method.