Pregnancy Effect on Echocardiographic Parameters in Great Dane Bitches

摘要

In women, as well as in bitches, pregnancy is associated with the adaptation of the left ventricular function. Pregnancy mainly represents a status of increased volume load of the maternal heart driven by the need to supply an adequate blood flow through an augmented uterine perfusion to the developing fetuses. Consequently, cardiac morpho-functional changes are expected. Cardiac morphology and function in pregnant bitches that would develop complications may differ from those with a normal outcome. Thus, the assessment of the maternal cardiovascular function may be a useful screening tool to detect pregnancy complications in dogs. Few studies investigated the cardiac maternal adaptation in different gestational ages in dogs. Breed is a known source of variation in echocardiographic values; hence, the cardiac performance during pregnancy may also be prone to a breed-related variation. For these purposes, due to possible breed-related variations in cardiac parameters and function, and to the specific predisposition for myocardial diseases, echocardiographic changes along pregnancy in healthy Great Dane bitches were evaluated. A significant effect of the age of gestation on the increase of functional and diastolic parameters and on the decrease of systolic parameters was reported.