Nano Chromium Picolinate Improves Gene Expression Associated with Insulin Signaling in Porcine Skeletal Muscle and Adipose Tissue

摘要

Dietary chromium has been shown to reduce fat deposition and improve insulin action whereas dietary fat can increase fat deposition and cause insulin resistance. This study found that dietary nanoparticles of chromium picolinate, an organic form of chromium, caused changes in the genes involved in insulin action in both muscle and fat tissue that indicated improved insulin action. Conversely, a moderate increase in dietary fat caused changes consistent with increased fat deposition and reduced insulin action. In conclusion, nanoparticles of chromium picolinate offer a means of supplementing pigs diets to improve growth performance and carcass composition.