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Evaluation of a novel monoclonal antibody mAb109 by immuno-PET/fluorescent imaging for noninvasive lung adenocarcinoma diagnosis

机译：通过免疫宠物/荧光成像对新型单克隆抗体MAB109进行非侵入性肺腺癌诊断的评价

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摘要

Expression, purification of and characterization of mAb109. a Schematic representation of mAb109 production process. b Reduced and nonreduced SDS-PAGE (8%) analysis of purified mAb109. Molecular weight markers are shown on right. c MALDI-TOF analysis of purified mAb109 antibody. d Western blots of Prdx1 in A549 tumor cells

机译：MAB109的表达，纯化和表征。 MAB109生产过程的示意图。 B减少和无后的SDS-PAGE（8％）纯化MAB109分析。分子量标记显示在右侧。 C纯化MAB109抗体的MALDI-TOF分析。 A549肿瘤细胞中PRDX1的Western印迹

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期刊名称 Acta Pharmacologica Sinica
作者
Hua Zhu; Te-li Liu; Chang-hao Liu; Jing Wang; Hong Zhang; Bin Dong; Jing Shen; Chuan-ke Zhao; Zhen-fu Li; Zhen Cheng; Zhi Yang;
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作者单位

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年(卷),期 2020(41),1
年度 2020
页码 101–109
总页数 9
原文格式 PDF
正文语种
中图分类药学;
关键词
human lung adenocarcinoma;

机译：人肺腺癌;

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专利

1. Evaluation of a novel monoclonal antibody mAb109 by immuno-PET/fluorescent imaging for noninvasive lung adenocarcinoma diagnosis [J] . Hua Zhu, Zhen Cheng, Zhi Yang, 中国药理学报：英文版 . 2020,第001期

机译：通过免疫PET /荧光成像评估新型单克隆抗体mAb109在无创肺腺癌诊断中的作用
2. Synthesis and Evaluation of a Zr-89-Labeled Monoclonal Antibody for Immuno-PET Imaging of Amyloid-beta Deposition in the Brain [J] . Fissers Jens, Waldron Ann-Marie, De Vijlder Thomas, Molecular imaging and biology: MIB : the official publication of the Academy of Molecular Imaging . 2016,第4期

机译：Zr-89标签的单克隆抗体的合成和评价，用于大脑中淀粉样β沉积的免疫PET成像
3. WT1, monoclonal CEA, TTF1, and CA125 antibodies in the differential diagnosis of lung, breast, and ovarian adenocarcinomas in serous effusions. [J] . Zhu W, Michael CW Diagnostic cytopathology . 2007,第6期

机译：WT1，单克隆CEA，TTF1和CA125抗体可用于浆液性积液中肺，乳腺和卵巢腺癌的鉴别诊断。
4. Photodetection of early cancer in the upper aerodigestive tract and the bronchi using photofrin II and colorectal adenocarcinoma with fluoresceinated monoclonal antibodies [C] . Author(s): Georges Wagnieres Ecole Polytechnique Federale de Lausanne Lausanne Switzerland, Daniel Braichotte Ecole Polytechnique Federale de Lausanne Lausanne Switzerland, Andre Chatelain Ecole Polytechnique Federale de Lausanne Lausanne Switzer Future Trends in Biomedical Applications of Lasers . 1991

机译：使用Photofrin II和结直肠腺癌以及荧光素单克隆抗体对上呼吸道和支气管中的早期癌症进行光检测
5. Design, synthesis and validation of Axl-targeted monoclonal antibody probe for microPET imaging of human lung cancer. [D] . Guo, Jiacong. 2013

机译：针对人类肺癌的microPET成像的Axl靶向单克隆抗体探针的设计，合成和验证。
6. Malignant mesotheliomas. Improved differential diagnosis from lung adenocarcinomas using monoclonal antibodies 44-3A6 and 624A12. [O] . I. Lee, J. A. Radosevich, G. Chejfec, 1986

机译：恶性间皮瘤。使用单克隆抗体44-3A6和624A12改善了肺腺癌的鉴别诊断。
7. Immunohistochemical evaluation of seven monoclonal antibodies for differentiation of pleural mesothelioma from lung adenocarcinoma [O] . Patricia R. Wirth, George L. Wright, Jacques Legier 1991

机译：肺腺癌胸腔间皮瘤分化七种单克隆抗体的免疫组化评价

Evaluation of a novel monoclonal antibody mAb109 by immuno-PET/fluorescent imaging for noninvasive lung adenocarcinoma diagnosis

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