Ipsilateral breast metastasis from lung adenocarcinoma harboring anaplastic lymphoma kinase or ROS1 rearrangement and significant response after targeted therapy: report of two cases

摘要

A 43-year-old female patient was admitted to our department for a 6-month-history of paroxysmal cough in July 2013. She was diagnosed with right lower lung adenocarcinoma (cT2aN3M1b, stage IV, anaplastic lymphoma kinase [ALK]+) with bone metastasis in other hospital and came to participate a phase III trial of crizotinib (No. ).