首页> 美国卫生研究院文献>The Journal of Clinical Investigation >Spleen cell transfusion in the Bio-Breeding/Worcester rat. Prevention of diabetes major histocompatibility complex restriction and long-term persistence of transfused cells.

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Spleen cell transfusion in the Bio-Breeding/Worcester rat. Prevention of diabetes major histocompatibility complex restriction and long-term persistence of transfused cells.

机译：在Bio-Breeding / Worcester大鼠中进行脾细胞输血。预防糖尿病严重的组织相容性复合物限制以及输血细胞的长期存留。

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摘要

We report that transfusions of RT1u Wistar-Furth (WF) spleen cells prevented spontaneous diabetes in the RT1u BB/W rat while RT1b Buffalo rat spleen cells did not. In addition, donor origin WF T lymphocytes were detected in nondiabetic-susceptible BB/W recipients 5 mo after transfusion. Survival of donor-origin lymphocytes may provide the cellular mechanism by which major histocompatibility complex-compatible WF spleen cell transfusions prevent BB rat diabetes.

机译：我们报道RT1u Wistar-Furth（WF）脾细胞的输血阻止了RT1u BB / W大鼠的自发性糖尿病，而RT1b Buffalo大鼠的脾细胞却没有。此外，输血后5 mo在非糖尿病易感BB / W接受者中检测到供体来源的WF T淋巴细胞。供体来源的淋巴细胞的存活可以提供主要的组织相容性复合物相容的WF脾细胞输血预防BB大鼠糖尿病的细胞机制。

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期刊名称 The Journal of Clinical Investigation
作者
A A Rossini; J P Mordes; D L Greiner; K Nakano; M C Appel; E S Handler;
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作者单位

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年(卷),期 1986(77),4
年度 1986
页码 1399–1401
总页数 3
原文格式 PDF
正文语种
中图分类医学史;
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专利

1. A major histocompatibility complex class II restriction for BioBreeding/Worcester diabetes-inducing T cells. [J] . K E Ellerman, A A Like The Journal of Experomental Medicine . 1995,第4期

机译：对BioBreeding / Worcester糖尿病诱导T细胞的主要组织相容性复合物II类限制。
2. Suppressor T-cell mechanisms in contact sensitivity. III. Apparent non-major histocompatibility complex restriction is a result of multiple sets of major histocompatibility complex-specific suppressor T cells induced by syngeneic 2,4-dinitrophenyl-modified lymphoid cells. [J] . S D Miller The Journal of Experomental Medicine . 1979,第3期

机译：抑制T细胞接触敏感性的机制。三，明显的非主要组织相容性复合物限制是同基因的2,4-二硝基苯基修饰的淋巴样细胞诱导的多组主要组织相容性复合物特异性抑制性T细胞的结果。
3. Minimum conditions of major histocompatibility complex compatibility and recipient immune compromise required to establish donor white blood cell persistence in a murine transfusion model. [J] . Lee TH, Wen L, Montalvo L, Transfusion: The Journal of the American Association of Blood Banks . 2005,第3期

机译：建立鼠输血模型中供体白细胞持久性所需的主要组织相容性复合物相容性和受体免疫折衷的最低条件。
4. Invariant chain regulates the major histocompatibility complex class II peptide repertoire of cell-based cancer vaccines. [C] . Olesya Y. Chornoguz, Lydia Grmai, Alexei Gapeev, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2010

机译：不变链调节细胞基癌症疫苗的主要组织相容性复合体II类肽曲目。
5. The major histocompatibility complex in mouse embryos and embryonic stem cells. [D] . Lampton, Paula Welter. 2008

机译：小鼠胚胎和胚胎干细胞中的主要组织相容性复合物。
6. Lymphocyte transfusions prevent diabetes in the Bio-Breeding/Worcester rat. [O] . A A Rossini, D Faustman, B A Woda, 1984

机译：淋巴细胞输注可预防Bio-Breeding / Worcester大鼠的糖尿病。
7. Spleen cell transfusion in the Bio-Breeding/Worcester rat. Prevention of diabetes, major histocompatibility complex restriction, and long-term persistence of transfused cells. [O] . Rossini, A A, Mordes, J P, Greiner, D L, 1986

机译：在Bio-Breeding / Worcester大鼠中进行脾细胞输血。预防糖尿病，严重的组织相容性复合物限制以及输血细胞的长期存留。
8. Role of the Major Histocompatibility Complex in T Cell Activation of B Cell Subpopulations, Lyb-5(+) and Lyb-5(-) B Cell Subpopulations Differ in Their Requirement for Major Histocompatibility Complex-Restricted T Cell Recognition [R] . Singer, A., Morrissey, P. J., Hathcock, K. S., 1981

机译：主要组织相容性复合物在B细胞亚群，Lyb-5（+）和Lyb-5（ - ）B细胞亚群的T细胞活化中的作用不同于它们对主要组织相容性复杂限制性T细胞识别的要求

Spleen cell transfusion in the Bio-Breeding/Worcester rat. Prevention of diabetes major histocompatibility complex restriction and long-term persistence of transfused cells.

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