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Terahertz Metamaterial with Multiple Resonances for Biosensing Application

机译:具有多种共振的太赫兹超材料用于生物传感应用

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摘要

A sickle-shaped metamaterial (SSM) based biochemical sensor with multiple resonances was investigated in the terahertz frequency range. The electromagnetic responses of SSM were found to be four resonances, namely dipolar, quadrupolar, octupolar and hexadecapolar plasmon resonances. They were generated from the interactions between SSM and perpendicularly incident terahertz waves. The sensing performances of SSM-based biochemical sensors were evaluated by changing ambient environments and analyte varieties. The highest values of sensitivity and figure of merit (FOM) for SSM covered with analyte thin-films were 471 GHz/RIU (refraction index unit) and 94 RIU , respectively. In order to further investigate the biosensing ability of the proposed SSM device, dielectric hemispheres and microfluidic chips were adopted to imitate dry and hydrous biological specimens, respectively. The results show that the sensing abilities of SSM-based biochemical sensors could be enhanced by increasing either the number of hemispheres or the channel width of the microfluidic chip. The highest sensitivity was 405 GHz/RIU for SSM integrated with microfluidic chips. Finally, three more realistic models were simulated to imitate real sensing situations, and the corresponding highest sensitivity was 502 GHz/RIU. The proposed SSM device paves the way to possible uses in biochemical sensing applications.
机译:在太赫兹频率范围内研究了基于镰刀形超材料(SSM)的具有多个共振的生化传感器。发现SSM的电磁响应是四个共振,即双极,四极,八极和十六极等离子体激元共振。它们是由SSM和垂直入射的太赫兹波之间的相互作用产生的。通过改变周围环境和分析物种类来评估基于SSM的生化传感器的传感性能。覆盖有分析物薄膜的SSM的最高灵敏度和品质因数(FOM)分别为471 GHz / RIU(折射率单位)和94 RIU。为了进一步研究所提出的SSM装置的生物传感能力,分别采用电介质半球和微流控芯片来模拟干燥和含水的生物样本。结果表明,通过增加半球的数量或微流控芯片的通道宽度,可以增强基于SSM的生化传感器的传感能力。对于集成有微流控芯片的SSM,最高灵敏度为405 GHz / RIU。最后,还模拟了另外三个逼真的模型来模拟实际的传感情况,相应的最高灵敏度为502 GHz / RIU。提议的SSM设备为生化传感应用的可能使用铺平了道路。

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