Changes in cross-frequency coupling following closed-loop auditory stimulation in non-rapid eye movement sleep

摘要

Closed-loop auditory stimulation protocol. During the STIM experimental nights, acoustic stimulation (50 ms bursts of 1/f pink noise, inter-stimuli interval ≥ 2 s) was delivered whenever the EEG signal crossed a threshold of  + 30 µV (dashed lines) in the electrode C4 electrode located over the right sensorimotor area (red electrode on the high-density EEG cap).