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Some properties of a simple stochastic epidemic model of SIR type

机译:SIR型简单随机流行病模型的一些性质

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摘要

We investigate the properties of a simple discrete time stochastic epidemic model. The model is Markovian of the SIR type in which the total population is constant and individuals meet a random number of other individuals at each time step. Individuals remain infectious for time units, after which they become removed or immune. Individual transition probabilities from susceptible to diseased states are given in terms of the binomial distribution. An expression is given for the probability that any individuals beyond those initially infected become diseased. In the model with a finite recovery time , simulations reveal large variability in both the total number of infected individuals and in the total duration of the epidemic, even when the variability in number of contacts per day is small. In the case of no recovery,  = ∞, a formal diffusion approximation is obtained for the number infected. The mean for the diffusion process can be approximated by a logistic which is more accurate for larger contact rates or faster developing epidemics. For finite we then proceed mainly by simulation and investigate in the mean the effects of varying the parameters (the probability of transmission), , and the number of contacts per day per individual. A scale invariant property is noted for the size of an outbreak in relation to the total population size. Most notable are the existence of maxima in the duration of an epidemic as a function of and the extremely large differences in the sizes of outbreaks which can occur for small changes in . These findings have practical applications in controlling the size and duration of epidemics and hence reducing their human and economic costs.
机译:我们研究了一个简单的离散时间随机流行模型的性质。该模型是SIR类型的马尔可夫模型,其中总人口是恒定的,并且每个时间步长的个体都遇到随机数的其他个体。个体在时间单位上仍具有传染性,在此之后他们将被移走或免疫。从易感状态到患病状态的个体过渡概率以二项式分布给出。表示最初感染者以外的任何个体患病的可能性。在具有有限恢复时间的模型中,即使每天接触数量的变化很小,模拟也显示出受感染个体的总数和流行病的总持续时间均存在较大的变化。在无恢复的情况下(=∞),获得感染数量的形式扩散近似值。扩散过程的平均值可以通过逻辑对数近似,对于更大的接触率或更快的流行病,逻辑对数更准确。对于有限,然后我们主要通过仿真进行,并研究均值改变参数(传输的概率)的影响,以及每个人每天的联系数量。爆发规模相对于总种群规模的规模不变属性被记录下来。最显着的是流行病持续期间最大值的存在与爆发的大小的极大差异,爆发的规模可能因微小的变化而发生。这些发现在控制流行病的大小和持续时间,从而减少其人力和经济成本方面具有实际应用价值。

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