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Ultrasensitive Surface Plasmon Resonance Biosensor Using Blue Phosphorus–Graphene Architecture

机译:使用蓝磷-石墨烯架构的超灵敏表面等离子体共振生物传感器

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摘要

This study theoretically proposed a novel surface plasmon resonance biosensor by incorporating emerging two dimensional material blue phosphorus and graphene layers with plasmonic gold film. The excellent performances employed for biosensing can be realized by accurately tuning the thickness of gold film and the number of blue phosphorus interlayer. Our proposed plasmonic biosensor architecture designed by phase modulation is much superior to angular modulation, providing 4 orders of magnitude sensitivity enhancement. In addition, the optimized stacked configuration is 42 nm Au film/2-layer blue phosphorus /4-layer graphene, which can produce the sharpest differential phase of 176.7661 degrees and darkest minimum reflectivity as low as 5.3787 × 10 . For a tiny variation in local refractive index of 0.0012 RIU (RIU, refractive index unit) due to the binding interactions of aromatic biomolecules, our proposed biosensor can provide an ultrahigh detection sensitivity up to 1.4731 × 10 °/RIU, highly promising for performing ultrasensitive biosensing application.
机译:这项研究从理论上提出了一种新型的表面等离振子共振生物传感器,它将新兴的二维材料蓝磷和石墨烯层与等离激子金膜结合在一起。通过精确调节金膜的厚度和蓝磷中间层的数量,可以实现用于生物传感的出色性能。我们提出的通过相位调制设计的等离激元生物传感器架构比角度调制要好得多,可提供4个数量级的灵敏度增强。此外,优化的堆叠结构是42 nm Au膜/ 2层蓝磷/ 4层石墨烯,可产生最清晰的微分相位176.7661度和最暗的最小反射率,低至5.3787×10。由于芳香族生物分子之间的相互作用,局部折射率只有0.0012 RIU(RIU,折射率单位)的微小变化,我们提出的生物传感器可以提供高达1.4731×10°/ RIU的超高检测灵敏度,非常有可能实现超高灵敏度生物传感应用。

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