Dorsal Hippocampus ERK2 Signaling Mediates Anxiolytic-RelatedBehavior in Male Rats

摘要

Anxiety disorders are the most common neuropathologies worldwide, but theprecise neuronal mechanisms that underlie these disorders remain unknown.The hippocampus plays a role in mediating anxiety-related responses, whichcan be modeled in rodents using behavioral assays, such as the elevated plusmaze. Yet, the molecular markers that underlie affect-related behavior onthe elevated plus maze are not well understood.