Reduction of PaCO2 by high-flow nasal cannula in acute hypercapnic respiratory failure patients receiving conventional oxygen therapy

摘要

It has been suggested that a high-flow nasal cannula (HFNC) could help to remove carbon dioxide (CO ) from anatomical dead spaces, but evidence to support that is lacking. The objective of this study was to elucidate whether use of an HFNC could reduce the arterial partial pressure of CO (PaCO ) in patients with acute hypercapnic respiratory failure who are receiving conventional oxygen (O ) therapy.