首页> 美国卫生研究院文献>Maternal Child Nutrition >Effect of complementary feeding with lipid‐based nutrient supplements and corn–soy blend on the incidence of stunting and linear growth among 6‐ to 18‐month‐old infants and children in rural Malawi
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Effect of complementary feeding with lipid‐based nutrient supplements and corn–soy blend on the incidence of stunting and linear growth among 6‐ to 18‐month‐old infants and children in rural Malawi

机译:马拉维农村地区以脂为基础的营养补充剂和玉米大豆混合饲料补充喂养对6至18个月大婴儿和儿童发育迟缓和线性生长的发生率的影响

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摘要

Low nutritional value of complementary foods is associated with high incidence of childhood growth stunting in low‐income countries. This study was done to test a hypothesis that dietary complementation with lipid‐based nutrient supplements ( ) promotes linear growth and reduces the incidence of severe stunting among at‐risk infants. A total of 840 6‐month‐old healthy infants in rural alawi were enrolled to a randomised assessor‐blinded trial. The participants received 12‐month supplementation with nothing, milk– , soy– , or corn–soy blend ( ). Supplements provided micronutrients and approximately 280 kcal energy per day. Outcomes were incidence of severe and very severe stunting [length‐for‐age ‐score, ( ) LAZ. The incidence of severe stunting was 11.8%, 8.2%, 9.1% and 15.5% (  = 0.098) and that of very severe stunting 7.4%, 2.9%, 8.0% and 6.4% (  = 0.138) in control, milk– , soy– and groups, respectively. Between 9 and 12 months of age, the mean change in was −0.15, −0.02, −0.12 and −0.18 (  = 0.045) for control, milk– , soy– and groups, respectively. There was no significant between‐group difference in linear growth during other age‐intervals. Although participants who received milk– had the lowest incidence of severe and very severe stunting, the differences between the groups were smaller than expected. Thus, the results do not provide conclusive evidence on a causal association between the supplementation and the lower incidence of stunting. Exploratory analyses suggest that provision of milk– , but not soy– promotes linear growth among at‐risk infants mainly between 9 and 12 months of age.
机译:补充食品的营养价值低与低收入国家儿童发育迟缓的高发率有关。这项研究是为了检验以下假设,即膳食补充以脂质为基础的营养补充剂可促进线性生长并降低高危婴儿严重发育迟缓的发生率。农村阿拉维地区共有840名6个月大的健康婴儿参加了一项随机评估者盲试验。参与者接受了为期12个月的补充食品,其中没有牛奶,大豆或玉米大豆混合饲料()。补品每天提供微量营养素和大约280大卡的热量。结果是严重的和非常严重的发育不良[年龄-年龄分数,()LAZ。对照,牛奶,大豆,大豆,大豆,大豆,大豆,大豆和大豆的严重发育迟缓的发生率分别为11.8%,8.2%,9.1%和15.5%(= 0.098),非常严重发育迟缓的发生率分别为7.4%,2.9%,8.0%和6.4%(= 0.138)。和组。在9至12个月大时,对照组,牛奶,大豆和对照组的平均变化分别为-0.15,-0.02,-0.12和-0.18((= 0.045)。在其他年龄间隔内,线性增长的组间差异无统计学意义。尽管接受牛奶的参与者发生严重和非常严重的发育迟缓的发生率最低,但是两组之间的差异小于预期。因此,结果并未提供关于补充与较低的发育不良发生率之间因果关系的确凿证据。探索性分析表明,提供牛奶(但不提供大豆)促进主要在9至12个月大的高危婴儿中线性生长。

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