The construction of a panel of serum amino acids for the identification of early chronic kidney disease patients

摘要

Serum creatinine, urea, and cystatin‐c are standardly used for the evaluation of renal function in the clinic. However, some patients have chronic kidney disease but still retain kidney function; a conventional serum index in these patients can be completely normal. Serum amino acid levels can reflect subtle changes in metabolism and are closely related to renal function. Here, we investigated how amino acids change as renal impairment increases.