QT Interval Prolongation in End‐Stage Liver Disease Cannot Be Explained by Nonhepatic Factors

摘要

QT interval prolongation in patients with end‐stage liver disease (ESLD) is common. However, electrolyte abnormalities, renal insufficiency, treatment with QT‐prolonging drugs, and other factors known to prolong QT interval independently of liver disease occur frequently in ESLD. Moreover, elevated heart rate may be present in ESLD and result in spurious QTc prolongation if the Bazett formula is used for rate correction. It thus remains unclear whether QT prolongation in ESLD is directly caused by liver failure, or indirectly by these confounding factors.