What Percent Luminal Stenosis Should Be Used to Define Angiographic Coronary Artery Disease for Noninvasive Test Evaluation?

摘要

There has been controversy over what is the best angiographic luminal dimension criterion associated with ischemia for evaluating diagnostic tests. If one assumes that ST‐segment depression or scores are indicators of ischemia, then whatever angiographic criteria best discriminates those with ischemic and nonischemic responses would be the best angiographic marker for ischemia. To study this, we calculated the area under the ROC curves for ST depression and scores at different angiographic cut‐points in order to determine the best angiographic cut‐point for defining ischemia‐producing coronary disease.