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Maternal plasma genome-wide cell-free DNA can detect fetal aneuploidy in early and recurrent pregnancy loss and can be used to direct further workup

机译：母体血浆全基因组的无细胞DNA可以检测早期和反复妊娠流产中的胎儿非整倍性可用于指导进一步的检查

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摘要

Can maternal plasma cell-free DNA (cfDNA) detect chromosomal anomalies in early pregnancy loss (EPL) and recurrent pregnancy loss (RPL)?

机译：孕妇血浆无细胞DNA（cfDNA）能否检测出早期妊娠丢失（EPL）和反复妊娠丢失（RPL）中的染色体异常？

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期刊名称 Human Reproduction (Oxford England)
作者
Yuval Yaron; Montse Pauta; Celia Badenas; Anna Soler; Virginia Borobio; Carmen Illanes; Fernanda Paz-y-Miño; Raigam Martinez-Portilla; Antoni Borrell;
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作者单位

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年(卷),期 -1(35),5
年度 -1
页码 -1
总页数 8
原文格式 PDF
正文语种
中图分类妇产科学;生理学;
关键词
cell-free DNA; noninvasive; recurrent pregnancy loss; aneuploidy; chromosome anomalies;

机译：无细胞DNA;无创;复发性流产;非整倍性;染色体异常;
入库时间 2022-08-21 11:46:26

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专利

1. Maternal plasma genome-wide cell-free DNA can detect fetal aneuploidy in early and recurrent pregnancy loss and can be used to direct further workup [J] . Yaron Yuval, Pauta Montse, Badenas Celia, Trends in Ecology & Evolution . 2020,第5期

机译：母体血浆基因组宽的细胞DNA可以在早期和复发性妊娠损失中检测胎儿非整倍性，并可用于指示进一步的工作
2. Maternal plasma cell-free fetal and maternal DNA at 11-13 weeks' gestation: Relation to fetal and maternal characteristics and pregnancy outcomes [J] . PoonL.C.Y., MusciT., SongK., Fetal diagnosis and therapy . 2013,第4期

机译：孕11-13周时母体无细胞胎儿和母体DNA：与胎儿和母体特征及妊娠结局的关系
3. Non-invasive prenatal diagnosis of fetal aneuploidies using massively parallel sequencing-by-ligation and evidence that cell-free fetal DNA in the maternal plasma originates from cytotrophoblastic cells [J] . Brigitte HW Faas, Joep de Ligt, Irene Janssen, Expert opinion on biological therapy . 2012,第S1期

机译：非结扎性胎儿非整倍体的非侵入性产前诊断，采用大规模平行依测序法进行，并证明母体血浆中无细胞的胎儿DNA来源于滋养细胞
4. Detection of Fetal Single Gene Mutations through Targeted Sequencing of Maternal cell-free DNA [C] . Junghyun Namkung IEEE International Conference on Bioinformatics and Biomedicine . 2020

机译：通过母细胞无细胞DNA靶向测序检测胎儿单基因突变
5. Massively Parallel Sequencing of Cell-free DNA in Maternal Plasma: Biological Profiling and Clinical Applications. [D] . Yu, Cheuk Yin Jandy. 2014

机译：母体血浆中无细胞DNA的大规模并行测序：生物学分析和临床应用。
6. A Method to Quantify Cell-Free Fetal DNA Fraction in Maternal Plasma Using Next Generation Sequencing: Its Application in Non-Invasive Prenatal Chromosomal Aneuploidy Detection [O] . Xu-Ping Xu, Hai-Yan Gan, Fen-Xia Li, 2011

机译：一种使用下一代测序技术量化母体血浆中无细胞胎儿DNA比例的方法：其在非侵入性产前染色体非整倍性检测中的应用
7. Maternal plasma genome-wide cell-free DNA can detect fetal aneuploidy in early and recurrent pregnancy loss and can be used to direct further workup [O] . Yuval Yaron, Montse Pauta, Celia Badenas, 2020

机译：母体血浆基因组宽的细胞DNA可以在早期和复发性妊娠损失中检测胎儿非整倍性，可用于指示进一步的工作

Maternal plasma genome-wide cell-free DNA can detect fetal aneuploidy in early and recurrent pregnancy loss and can be used to direct further workup

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