Pten haploinsufficiency disrupts scaling across brain areas during development in mice

摘要

Total brain volume at P7 and P60. Absolute volume of GM and WM at P7 and P60. Relative volume of GM and WM at P7 and P60. , Magnetic resonance imaging fly-through of absolute ( ) and relative ( ) volume differences in mice at P7 and P60. Relative volume difference between and mice [( volume) – ( volume)/( volume) × 100] at P7 (green) and P60 (blue) in individual GM (gray backfill), WM (white backfill), and ventricular (pale violet backfill) brain regions. Green symbols indicate differences at P7, blue symbols indicate differences at P60. ***  p p p