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Bioaccumulation of Polycyclic Aromatic Hydrocarbon (PAH) in a bivalve (Arca senilis- blood cockles) and health risk assessment

机译:双壳类动物中的多环芳烃(PAH)的生物积累和健康风险评估

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摘要

Concentration of PAH in bivalves ( ) and human health risks due to consumption was examined in samples collected from southern Nigeria and analysed using gas chromatography. Mean PAH concentration (ngkg ) ranged from 12.0 ± 5.0–5500.0 ± 1000 with a significant difference (p −1) of PAH4 varied from 250 to 15268.0 while concentrations of PAH8 ranged from 542.0 to 15620.7 with significant difference (p −1) varied from 0.012 to 900.0 for individual PAH while carcinogenic toxic equivalent (TEQs) values were 1916.2, 572.49 and 1914.4 for total PAH, PAH4 and PAH8 respectively. The Excess cancer risk (ECR) for individual PAHs, PAH4 and PAH8 were all <10 . DDI and ECR values obtained were below USEPA threshold concentration/limits indicating minimal health risk concerns while PAH4 and PAH8 concentrations were also below the EU regulatory limits (30 μg kg ) for PAH4. The margin of exposures were above the 10,000 critical limit proposed by EFSA while incremental life cancer risk (ILCR) value (10 - 10 ) also suggests low potential health risk for consumers of the sea food. The screening value (SV) was 0.095 but lower than observed TEQs values indicating potential health concerns. The study concluded that consumers of bivalves ( in southern Nigeria generally have minimal health risk concern via consumption but regular monitoring is required to detect changes.
机译:从尼日利亚南部收集的样品中检查了双壳类动物体内PAH的浓度()和由于食用引起的人类健康风险,并使用气相色谱法进行了分析。平均PAH浓度(ngkg)为12.0±5.0–5500.0±1000,PAH4的显着性差异(p -1)为250至15268.0,而PAH8的浓度为542.0至15620.7的显着性差异(p -1)为单个PAH的0.012至900.0,而总PAH,PAH4和PAH8的致癌毒性当量(TEQ)值分别为1916.2、572.49和1914.4。个别PAH,PAH4和PAH8的过度癌症风险(ECR)均<10。获得的DDI和ECR值低于USEPA阈值浓度/限值,表明对健康风险的关注最小,而PAH4和PAH8的浓度也低于PAH4的欧盟法规限值(30μgkg千克)。暴露裕度高于EFSA提出的10,000临界限值,而生命癌症风险(ILCR)的增量值(10-10)也表明海鲜消费者的潜在健康风险较低。筛查值(SV)为0.095,但低于观察到的TEQs值,表明潜在的健康隐患。该研究得出的结论是,双壳类动物的消费者(在尼日利亚南部通常通过食用而对健康风险的关注最小,但需要定期监测以发现变化。

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