T117. FUNCTIONAL TRAJECTORY IN FIRST-EPISODE PSYCHOSIS BASED ON PREMORBID IQ AND AGE OF ONSET

摘要

Early age of onset of psychotic symptoms has been associated with poor functional prognosis in individuals with a first episode of psychosis before the age of 18 (EOP) in comparison with adult onset of psychosis (i.e. after age of 18; AOP; Immonen et al., 2017). Premorbid intelligence quotient (pIQ), which has shown to play an important role over longitudinal functioning (Bombin et al., 2013), is one of the factors that has been associated with age of onset (AO) in schizophrenia (Khandaker et al., 2011). However, in FEP individuals the relationship between premorbid pIQ and AO and the effect of both factors over clinical and functional outcomes has not yet been clarified. To clarify this issue, the present study aims to characterize FEP individuals in subgroups based on the former variables: premorbid IQ and age-of-onset and to examine functional and clinical trajectories of participants at two years follow-up.