5.4 INDIVIDUALIZED PREDICTION OF FUNCTIONAL OUTCOMES IN SCHIZOPHRENIA PATIENTS IN RESPONSE TO NEURO-COGNITIVE INTERVENTION: A MACHINE LEARNING ANALYSIS

摘要

Computer-based neurocognitive interventions (cNCI) represent an innovative way to improve cognitive functioning and functional outcome in schizophrenia patients. However, evidence suggests that cNCI can be highly effective in some, though not all patients. This variability is most likely due to intermediate neurocognitive and brain phenotypes that moderate the neuroplastic response induced by the respective training paradigms.