首页> 美国卫生研究院文献>Schizophrenia Bulletin >O11.2. CHARACTERIZING CANNABINOID INDUCED ACUTE PERSISTENT PSYCHOSIS (CIAPP) AS A POSSIBLE SUBTYPE OF SCHIZOPHRENIA USING DEEP LEARNING
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O11.2. CHARACTERIZING CANNABINOID INDUCED ACUTE PERSISTENT PSYCHOSIS (CIAPP) AS A POSSIBLE SUBTYPE OF SCHIZOPHRENIA USING DEEP LEARNING

机译:O11.2。通过深度学习将大麻素诱导的急性持久性精神病(CIAPP)表征为精神分裂症的一种可能亚型

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摘要

The schizophrenia syndrome likely encompasses multiple clinically related illness manifestations that result from distinct etio-pathological processes converging onto fewer final common pathways. Exposure to cannabis is known to result in a syndrome that clinically mimics schizophrenia-psychosis, outlasts the acute intoxication, persists for days to weeks, requires clinical intervention, and may recur with cannabis exposure. Characterizing the vulnerability to Cannabinoid Induced Acute and Persistent Psychosis (CIAPP), its clinical and neuro-physiological correlates, and its relationship to schizophrenia may enhance our understanding of the neurobiology of schizophrenia in general and specifically, this subtype. Deep learning is an extremely powerful approach to classify (e.g., cancerous vs healthy cells) and use complex stimuli to anticipate future outcomes (e.g., hurricane path) with high accuracy. Thus, deep learning seems a promising approach to differentiate subtypes of complex syndromes such as schizophrenia.
机译:精神分裂症综合征可能包含多种临床相关疾病表现,这些疾病表现是由独特的病因-病理过程融合到较少的最终共同途径中引起的。已知接触大麻会导致临床上模仿精神分裂症-精神病,持续急性中毒,持续数天至数周,需要临床干预并可能因接触大麻而复发的综合症。表征大麻素诱发的急性和持续性精神病(CIAPP)的脆弱性,其临床和神经生理学相关性及其与精神分裂症的关系,可能会增强我们对精神分裂症的神经生物学的整体了解,尤其是对这种亚型的了解。深度学习是一种非常强大的方法,可以进行分类(例如癌细胞还是健康细胞)并使用复杂的刺激来高精度地预测未来的结果(例如飓风路径)。因此,深度学习似乎是区分诸如精神分裂症等复杂综合症亚型的有前途的方法。

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