FARP1 boosts CDC42 activity from integrin αvβ5 signaling and correlates with poor prognosis of advanced gastric cancer

摘要

List of Rho GEF genes significantly correlated with poor prognosis of patients with gastric cancer. Relationship between expression and overall survival of patients with gastric cancer as assessed using the Kaplan–Meier plotter. Gene expression of in solid normal tissue and primary gastric cancer. Magnification, ×200; scale bar, 200 μm. Intensity of anti-FARP1 staining in the cytoplasm of gastric cancer cells. Overall survival of patients with gastric cancer within high and low FARP1 expression grouped according to immunohistochemistry assessment. Survival rates were calculated by the Kaplan–Meier method, and differences in survival were estimated by the log-rank test.